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ea0090rc8.3 | Rapid Communications 8: Calcium and Bone | ECE2023

CYP24A1 mutation as a rare cause of hypercalcemia during pregnancy

Kullamaa Liisa , SOderlund Sanni , Viukari Marianna , Matikainen Niina , Schalin-Jantti Camilla

Clinical case: A 27-year-old pregnant woman (24 weeks of gestation) was investigated as her Hb level (87 g/l) was low. Laboratory work-up revealed severe, non-PTH dependent hypercalcemia (see Table). This was her first pregnancy, and serum calcium measured once previously 12 years earlier had been normal. The patient had symptoms of increased thirst, constipation and hyperemesis.Diagnostic work up and Treatment: Rehydration and close mon...